| Species : |
Human |
| Source : |
Human |
| Tag : |
Non |
| Protein Length : |
81-210 a.a. |
| Description : |
NTF4, also known as neurotrophin 4, is a member of a family of neurotrophic factors neurotrophins that control survival and differentiation of mammalian neurons. This protein is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derivedneurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF4-deficient mice only show minor cellular deficits and develop normally to adulthood. |
| Form : |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 20% glycerol |
| Molecular Weight : |
14.1 kDa (131aa) |
| Purity : |
> 85% by SDS - PAGE |
| Concentration : |
1 mg/ml (determined by Bradford assay) |
| Sequences of amino acids : |
MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A |
| Storage : |
Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Pathways : |
MAPK signaling pathway; Neurotrophin signaling pathway |