Recombinant Human NTRK1 Protein, Fc/His-tagged NTRK1-2030H

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

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Recombinant Human NTRK1 Protein, Fc/His-tagged

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Cat.No. : NTRK1-2030H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human TrkA Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala33-Glu407) of human TrkA (Accession #NP_001012331.1) fused with an Fc, 6×His tag at the C-terminus.
Description : This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Source : HEK293
Species : Human
Tag : Fc/His
Form : Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
Protein length : Ala33-Glu407
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : > 90% as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ]
Official Symbol : NTRK1
Synonyms : NTRK1; neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; MTC; TRK; TRKA; gp140trk; Oncogene TRK; tyrosine kinase receptor A; tropomyosin-related kinase A; TRK1-transforming tyrosine kinase protein; TRK1; Trk-A; p140-TrkA; DKFZp781I14186;
Gene ID : 4914
mRNA Refseq : NM_001007792
Protein Refseq : NP_001007793
MIM : 191315
UniProt ID : P04629
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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