- Human(4)
- Mouse(1)
- Rhesus Macaque(1)
- Zebrafish(1)
Recombinant Human OCRL Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | OCRL-5112H |
| Product Overview : | OCRL MS Standard C13 and N15-labeled recombinant protein (NP_000267) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 104 kDa |
| AA Sequence : | MEPPLPVGAQ PLATVEGMEM KGPLREPCAL TLAQRNGQYE LIIQLHEKEQ HVQDIIPINS HFRCVQEAEE TLLIDIASNS GCKIRVQGDW IRERRFEIPD EEHCLKFLSA VLAAQKAQSQ LLVPEQKDSS SWYQKLDTKD KPSVFSGLLG FEDNFSSMNL DKKINSQNQP TGIHREPPPP PFSVNKMLPR EKEASNKEQP KVTNTMRKLF VPNTQSGQRE GLIKHILAKR EKEYVNIQTF RFFVGTWNVN GQSPDSGLEP WLNCDPNPPD IYCIGFQELD LSTEAFFYFE SVKEQEWSMA VERGLHSKAK YKKVQLVRLV GMMLLIFARK DQCRYIRDIA TETVGTGIMG KMGNKGGVAV RFVFHNTTFC IVNSHLAAHV EDFERRNQDY KDICARMSFV VPNQTLPQLN IMKHEVVIWL GDLNYRLCMP DANEVKSLIN KKDLQRLLKF DQLNIQRTQK KAFVDFNEGE IKFIPTYKYD SKTDRWDSSG KCRVPAWCDR ILWRGTNVNQ LNYRSHMELK TSDHKPVSAL FHIGVKVVDE RRYRKVFEDS VRIMDRMEND FLPSLELSRR EFVFENVKFR QLQKEKFQIS NNGQVPCHFS FIPKLNDSQY CKPWLRAEPF EGYLEPNETV DISLDVYVSK DSVTILNSGE DKIEDILVLH LDRGKDYFLT ISGNYLPSCF GTSLEALCRM KRPIREVPVT KLIDLEEDSF LEKEKSLLQM VPLDEGASER PLQVPKEIWL LVDHLFKYAC HQEDLFQTPG MQEELQQIID CLDTSIPETI PGSNHSVAEA LLIFLEALPE PVICYELYQR CLDSAYDPRI CRQVISQLPR CHRNVFRYLM AFLRELLKFS EYNSVNANMI ATLFTSLLLR PPPNLMARQT PSDRQRAIQF LLGFLLGSEE DTRTRPLEQK LISEEDLAAN DILDYKDDDD KV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | OCRL oculocerebrorenal syndrome of Lowe [ Homo sapiens (human) ] |
| Official Symbol : | OCRL |
| Synonyms : | OCRL; oculocerebrorenal syndrome of Lowe; inositol polyphosphate 5-phosphatase OCRL-1; OCRL1; Lowe oculocerebrorenal syndrome protein; phosphatidylinositol polyphosphate 5-phosphatase; LOCR; NPHL2; INPP5F; OCRL-1; |
| Gene ID : | 4952 |
| mRNA Refseq : | NM_000276 |
| Protein Refseq : | NP_000267 |
| MIM : | 300535 |
| UniProt ID : | Q01968 |
◆ Recombinant Protein
| OCRL-1442H | Recombinant Human OCRL, His-tagged | +Inquiry |
| OCRL-11068M | Recombinant Mouse OCRL Protein | +Inquiry |
| OCRL-3154R | Recombinant Rhesus monkey OCRL Protein, His-tagged | +Inquiry |
| OCRL-4845Z | Recombinant Zebrafish OCRL | +Inquiry |
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◆ Lysates
| OCRL-3601HCL | Recombinant Human OCRL 293 Cell Lysate | +Inquiry |
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