Recombinant Human OTUD5 Protein, MYC/DDK-tagged OTUD5-373H

Recombinant Human OTUD5 Protein, MYC/DDK-tagged

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Recombinant Human OTUD5 Protein, MYC/DDK-tagged

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Cat.No. : OTUD5-373H
Product Overview : Recombinant human OTUD5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 60.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : OTU deubiquitinase 5 [ Homo sapiens ]
Official Symbol : OTUD5
Synonyms : DUBA; DUBA
Gene ID : 55593
mRNA Refseq : NM_017602.3
Protein Refseq : NP_060072.1
MIM : 300713
UniProt ID : Q96G74

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