Recombinant Human OTUD5 Protein, MYC/DDK-tagged
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| Cat.No. : | OTUD5-373H |
| Product Overview : | Recombinant human OTUD5 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
| Description : | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | MYC/DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
| Molecular Mass : | 60.4 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name : | OTU deubiquitinase 5 [ Homo sapiens ] |
| Official Symbol : | OTUD5 |
| Synonyms : | DUBA; DUBA |
| Gene ID : | 55593 |
| mRNA Refseq : | NM_017602.3 |
| Protein Refseq : | NP_060072.1 |
| MIM : | 300713 |
| UniProt ID : | Q96G74 |
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