Recombinant Human PAK2 Protein, His-tagged

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Recombinant Human PAK2 Protein, His-tagged

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Cat.No. : PAK2-767H
Product Overview : Recombinant Human PAK2(Glu177~Ala419) fused with His tag at N-terminal was expressed in E. coli.
Description : The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 30.7kDa
Protein length : Glu177~Ala419
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 92%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others.
Figure :

Gene Name : PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 [ Homo sapiens ]
Official Symbol : PAK2
Synonyms : PAK2; p21 protein (Cdc42/Rac)-activated kinase 2; p21 (CDKN1A) activated kinase 2; serine/threonine-protein kinase PAK 2; PAK65; PAKgamma; S6/H4 kinase; p58; PAK-2; gamma-PAK; p21-activated kinase 2; p21 (CDKN1A)-activated kinase 2;
Gene ID : 5062
mRNA Refseq : NM_002577
Protein Refseq : NP_002568
MIM : 605022
UniProt ID : Q13177
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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