Recombinant Human PCSK6 protein, His-tagged

Cat.No. : PCSK6-3303H
Product Overview : Recombinant Human PCSK6 protein(Met168~Val487), fused with N-terminal His Tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 41kDa
Protein Length : Met168~Val487
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 90%
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Reconstitution : Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : PCSK6 proprotein convertase subtilisin/kexin type 6 [ Homo sapiens ]
Official Symbol : PCSK6
Synonyms : PCSK6; proprotein convertase subtilisin/kexin type 6; PACE4, paired basic amino acid cleaving system 4; SPC4; subtilisin like proprotein convertase 4; subtilisin like protease; subtilisin/kexin like protease PACE4; subtilisin/kexin-like protease PACE4; subtilisin-like proprotein convertase 4; paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; PACE4;
Gene ID : 5046
mRNA Refseq : NM_002570
Protein Refseq : NP_002561
MIM : 167405
UniProt ID : P29122

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does PCSK6 influence the activation of growth factors and hormones? 10/15/2022

It activates growth factors and hormones, influencing cell growth and differentiation.

What is the impact of altered PCSK6 activity in diseases like cancer? 08/28/2022

Altered PCSK6 activity is associated with cancer progression, impacting cell growth.

What role does PCSK6 play in developmental processes and organogenesis? 08/02/2021

PCSK6 is key in development, affecting organ formation and body patterning.

What is the primary function of PCSK6 in protein processing and regulation? 03/15/2021

PCSK6 activates precursor proteins into their active forms, essential for protein regulation.

How do genetic variations in PCSK6 affect its enzymatic activity and contribute to developmental disorders? 10/23/2020

Mutations in PCSK6 can disrupt protein processing, leading to developmental disorders.

How does PCSK6 interact with other proteases and signaling pathways in the cell? 05/07/2018

PCSK6 cooperates with other proteases, playing a role in various cellular pathways.

What potential therapeutic applications could arise from modulating PCSK6 activity in various diseases? 12/29/2017

Targeting PCSK6 could be therapeutic in conditions involving abnormal protein activation.

Customer Reviews (3)

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Reviews
03/20/2019

    Outstanding service. High-quality protein analysis.

    01/10/2019

      Top-notch support. Instrumental in our research achievements.

      03/26/2018

        Exceptional accuracy. Accelerates our research progress.

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