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- Rat(1)
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Recombinant Human PDE1B
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Cat.No. : | PDE1B-29995TH Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Full Length Human PDE1B,, with N terminal enzyme tag. MW= 87 kDa. Expressed in a Baculovirus infected Sf9 cell expression system. |
Description : | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 20mM Glutathione, 100mM Sodium chloride, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. |
Gene Name : | PDE1B phosphodiesterase 1B, calmodulin-dependent [ Homo sapiens ] |
Official Symbol : | PDE1B |
Synonyms : | PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDES1B; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B; |
Gene ID : | 5153 |
mRNA Refseq : | NM_000924 |
Protein Refseq : | NP_000915 |
MIM : | 171891 |
Uniprot ID : | Q01064 |
Chromosome Location : | 12q13 |
Pathway : | Ca-dependent events, organism-specific biosystem; CaM pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Calmodulin induced events, organism-specific biosystem; |
Function : | 3,5-cyclic-AMP phosphodiesterase activity; calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity; calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity; |
◆ Recombinant Protein
PDE1B-745H | Recombinant Human PDE1B Protein, MYC/DDK-tagged | +Inquiry |
PDE1B-042H | Recombinant Human PDE1B Protein, His/GST-tagged | +Inquiry |
PDE1B-04H | Recombinant Human PDE1B Protein, His/GST-tagged | +Inquiry |
Pde1b-4743M | Recombinant Mouse Pde1b Protein, Myc/DDK-tagged | +Inquiry |
PDE1B-1599H | Recombinant Human PDE1B, GST-tagged | +Inquiry |
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◆ Lysates
PDE1B-627HCL | Recombinant Human PDE1B cell lysate | +Inquiry |
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◆ Assay kits
Kit-1825 | PDE1B Assay Kit | +Inquiry |
Kit-1827 | PDE1B TR-FRET Assay Kit | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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