Recombinant Human PDE1B PDE1B-29995TH

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

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Recombinant Human PDE1B

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Cat.No. : PDE1B-29995TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant Full Length Human PDE1B,, with N terminal enzyme tag. MW= 87 kDa. Expressed in a Baculovirus infected Sf9 cell expression system.
Description : The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 20mM Glutathione, 100mM Sodium chloride, pH 8.0
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
Gene Name : PDE1B phosphodiesterase 1B, calmodulin-dependent [ Homo sapiens ]
Official Symbol : PDE1B
Synonyms : PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDES1B; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B;
Gene ID : 5153
mRNA Refseq : NM_000924
Protein Refseq : NP_000915
MIM : 171891
Uniprot ID : Q01064
Chromosome Location : 12q13
Pathway : Ca-dependent events, organism-specific biosystem; CaM pathway, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Calmodulin induced events, organism-specific biosystem;
Function : 3,5-cyclic-AMP phosphodiesterase activity; calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity; calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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