Recombinant Human PDE1B Protein, His/GST-tagged PDE1B-042H

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Recombinant Human PDE1B Protein, His/GST-tagged

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Cat.No. :	PDE1B-042H
Product Overview :	Recombinant N-terminal His-GST-tagged full length human PDE1B1 protein (1-536) was expressed in insect cells.
Description :	The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source :	Insect cell
Species :	Human
Tag :	His/GST
Form :	Lyophilized
Molecular Mass :	89.2 kDa
Protein length :	1-536
Endotoxin :	<1.0 EU/ μg, determined by the LAL endotoxin assay.
Purity :	≥94% estimated by SDS-PAGE
Stability :	≥ 1 year
Storage :	At -80 centigrade.
Storage Buffer :	Sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride
SDS-PAGE analysis of PDE1B1 :	Lane 1: MW Markers Lane 2: PDE1B1

Gene Name :	PDE1B phosphodiesterase 1B [ Homo sapiens (human) ]
Official Symbol :	PDE1B
Synonyms :	PDE1B; phosphodiesterase 1B; PDE1B1; PDES1B; HEL-S-79p; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; 63 kDa Cam-PDE; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; cam-PDE 1B; epididymis secretory sperm binding protein Li 79p; phosphodiesterase 1B, calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; EC 3.1.4.17
Gene ID :	5153
mRNA Refseq :	NM_000924
Protein Refseq :	NP_000915
MIM :	171891
UniProt ID :	Q01064