Recombinant Human PDE2A

Cat.No. : PDE2A-29979TH
Product Overview : Recombinant fragment of Human PDE2A (amino acids 850-940) with a N terminal proprietary tag; Predicted MWt 35.64 kDa including the tag.
  • Specification
  • Gene Information
  • Related Products
Description : cGMP-dependent 3,5-cyclic phosphodiesterase is an enzyme that in humans is encoded by the PDE2A gene.
Protein length : 91 amino acids
Molecular Weight : 35.640kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris buffered saline, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : REKAYIPELQISFMEHIAMPIYKLL QDLFPKAAELYERVASNREHWTKVS HKFTIRGLPSNNSLDFLDEEYEVPD LDGTRAPINGCCSLDA
Sequence Similarities : Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.Contains 2 GAF domains.
Gene Name : PDE2A phosphodiesterase 2A, cGMP-stimulated [ Homo sapiens ]
Official Symbol : PDE2A
Synonyms : PDE2A; phosphodiesterase 2A, cGMP-stimulated; cGMP-dependent 3,5-cyclic phosphodiesterase;
Gene ID : 5138
mRNA Refseq : NM_001143839
Protein Refseq : NP_001137311
MIM : 602658
Uniprot ID : O00408
Chromosome Location : 11q13.1-q14.1
Pathway : G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Hemostasis, organism-specific biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem;
Function : 3,5-cyclic-nucleotide phosphodiesterase activity; TPR domain binding; cAMP binding; cGMP binding; cGMP binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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