Recombinant Human PDE4B Protein, His/GST-tagged


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Recombinant Human PDE4B Protein, His/GST-tagged

PDE4B Related Products

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Cat.No. : PDE4B-147H
Product Overview : Recombinant human N-terminal His-GST-tagged PDE4B2 protein (1-564) was expressed in insect cells.
Description : This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
Source : Insect cell
Species : Human
Tag : His/GST
Form : Lyophilized
Molecular Mass : 92.2 kDa
Protein length : 1-564
Endotoxin : <1.0 EU/μg, determined by the LAL endotoxin assay
Purity : ≥80% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : At -80 centigrade.
Storage Buffer : Lyophilized from sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride, 0.5 mM GSH, 10% gly, and 0.5 mM PMSF
SDS-PAGE Analysis of PDE4B :

Lane 1: MW Markers
Lane 2: PDE2A (human, recombinant; aa 215-900)

Gene Name : PDE4B phosphodiesterase 4B [ Homo sapiens (human) ]
Official Symbol : PDE4B
Synonyms : PDE4B; phosphodiesterase 4B; DPDE4; PDEIVB; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; dunce-like phosphodiesterase E4; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); EC
Gene ID : 5142
mRNA Refseq : NM_001037339
Protein Refseq : NP_001032416
MIM : 600127
UniProt ID : Q07343
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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