"PDGFRA" Related Products


Recombinant Human PDGFRA Protein, Fc/His-tagged

Cat.No. : PDGFRA-2050H
Product Overview : Recombinant Human PDGFRa/CD140a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln24-Glu524) of human PDGFRa/CD140a (Accession #NP_006197.1) fused with an Fc, 6×His tag at the C-terminus.
Description : PDGFRA, i.e. platelet-derived growth factor receptor A, also termed PDGFRα, i.e. platelet-derived growth factor receptor α, is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. Mutations in the gene which codes for PDGFRA, i.e. the PDGFRA gene, are associated with an array of clinically significant neoplasms.
Source : HEK293
Species : Human
Tag : Fc/His
Form : Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol.
Protein length : Gln24-Glu524
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : > 90% as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : PDGFRA platelet-derived growth factor receptor, alpha polypeptide [ Homo sapiens ]
Official Symbol : PDGFRA
Synonyms : PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795;
Gene ID : 5156
mRNA Refseq : NM_006206
Protein Refseq : NP_006197
MIM : 173490
UniProt ID : P16234

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