Recombinant Human Pepsinogen I Protein

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Recombinant Human Pepsinogen I Protein

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Cat.No. : PGC-1028H
Product Overview : Recombinant Human pepsinogen I protein. Predicted molecular weight: 40 kDa.
Description : Pepsinogen is the pro-form of pepsin and is produced in the stomach by chief cells. The major part of pepsinogen is secreted into the gastric lumen but a small amount can be found in the blood. Alterations in the serum pepsinogen concentrations has been found with Helicobacter pylori (H. Pylori) infections, peptic ulcer disease, gastritis, and gastric cancer. More precise analysis may be achieved by measuring the pepsinogen I/II ratio.
Source : E. coli
Species : Human
Form : Lyophilized from 0.2 μm filtered solution
Bio-activity : Anti- h Pepsinogen I 8003 : + Anti- h Pepsinogen I 8015 : +
Molecular Mass : 40 kDa
AA Sequence : MIMYKVPLIR KKSLRRTLSE RGLLKDFLKK HNLNPARKYF PQWEAPTLVD EQPLENYLDM EYFGTIGIGT PAQDFTVVFD TGSSNLWVPS VYCSSLACTN HNRFNPEDSS TYQSTSETVS ITYGTGSMTG ILGYDTVQVG GISDTNQIFG LSETEPGSFL YYAPFDGILG LAYPSISSSG ATPVFDNIWN QGLVSQDLFS VYLSADDQSG SVVIFGGIDS SYYTGSLNWV PVTVEGYWQI TVDSITMNGE AIACAEGCQA IVDTGTSLLT GPTSPIANIQ SDIGASENSD GDMVVSCSAI SSLPDIVFTI NGVQYPVPPS AYILQSEGSC ISGFQGMNLP TESGELWILG DVFIRQYFTV FDRANNQVGL APVA
Storage : 2–8centigrade
Concentration : 0.5 mg/ml when reconstituted with 200 µl of deionized water
Storage Buffer : 50 mM Tris-HCl, pH 7.5; 150 mM NaCl, 0,5 µg/ml pepstatin A; containing 6 % sucrose as a stabilizer
Reconstitution : Reconstitute lyophilized protein with 200 µl of deionized water
Gene Name : PGC progastricsin (pepsinogen C) [ Homo sapiens ]
Official Symbol : PGC
Synonyms : PGC; progastricsin (pepsinogen C); gastricsin; pepsin C; pepsinogen C; preprogastricsin; pepsinogen group II; PEPC; PGII; FLJ99563;
Gene ID : 5225
mRNA Refseq : NM_001166424
Protein Refseq : NP_001159896
MIM : 169740
UniProt ID : P20142

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