Active Recombinant Human Pepsinogen I Protein

• Cat.No.: PGC-1028H
• Product Overview: Recombinant Human pepsinogen I protein. Predicted molecular weight: 40 kDa.

Specification

• Description: Pepsinogen is the pro-form of pepsin and is produced in the stomach by chief cells. The major part of pepsinogen is secreted into the gastric lumen but a small amount can be found in the blood. Alterations in the serum pepsinogen concentrations has been found with Helicobacter pylori (H. Pylori) infections, peptic ulcer disease, gastritis, and gastric cancer. More precise analysis may be achieved by measuring the pepsinogen I/II ratio.
• Source: E. coli
• Species: Human
• Form: Lyophilized from 0.2 μm filtered solution
• Bio-activity: Anti- h Pepsinogen I 8003 : + Anti- h Pepsinogen I 8015 : +
• Molecular Mass: 40 kDa
• AA Sequence: MIMYKVPLIRKKSLRRTLSERGLLK DFLKKHNLNPARKYFPQWEAPTLVD EQPLENYLDMEYFGTIGI GTPAQDFTVVFDTGSSNLWVPSVYC SSLACTNHNRFNPEDSSTYQSTSET VSITYGTGSMTGILGYD TVQVGGISDTNQIFGLSETEPGSFL YYAPFDGILGLAYPSISSSGATPVF DNIWNQGLVSQDLFSVYLS ADDQSGSVVIFGGIDSSYYTGSLNW VPVTVEGYWQITVDSITMNGEAIAC AEGCQAIVDTGTSLLTG PTSPIANIQSDIGASENSDGDMVVS CSAISSLPDIVFTINGVQYPVPPSA YILQSEGSCISGFQGMNLPT ESGELWILGDVFIRQYFTVFDRANN QVGLAPVA
• Storage: 2–8centigrade
• Concentration: 0.5 mg/ml when reconstituted with 200 µl of deionized water
• Storage Buffer: 50 mM Tris-HCl, pH 7.5; 150 mM NaCl, 0,5 µg/ml pepstatin A; containing 6 % sucrose as a stabilizer
• Reconstitution: Reconstitute lyophilized protein with 200 µl of deionized water

Gene Information

• Gene Name: PGC progastricsin (pepsinogen C) [ Homo sapiens ]
• Official Symbol: PGC
• Synonyms: PGC; progastricsin (pepsinogen C); gastricsin; pepsin C; pepsinogen C; preprogastricsin; pepsinogen group II; PEPC; PGII; FLJ99563
• Gene ID: 5225
• mRNA Refseq: NM_001166424
• Protein Refseq: NP_001159896
• MIM: 169740
• UniProt ID: P20142