Recombinant Human PHYKPL Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PHYKPL-721H
• Product Overview: AGXT2L2 MS Standard C13 and N15-labeled recombinant protein (NP_699204) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49.7 kDa
• AA Sequence: MAADQRPKADTLALRQRLISSSCRL FFPEDPVKIVRAQGQYMYDEQGAEY IDCISNVAHVGHCHPLVVQAAHEQN QVLNTNSRYLHDNIVDYAQRLSETL PEQLCVFYFLNSGSEANDLALRLAR HYTGHQDVVVLDHAYHGHLSSLIDI SPYKFRNLDGQKEWVHVAPLPDTYR GPYREDHPNPAMAYANEVKRVVSSA QEKGRKIAAFFAESLPSVGGQIIPP AGYFSQVAEHIRKAGGVFVADEIQV GFGRVGKHFWAFQLQGKDFVPDIVT MGKSIGNGHPVACVAATQPVARAFE ATGVEYFNTFGGSPVSCAVGLAVLN VLEKEQLQDHATSVGSFLMQLLGQQ KIKHPIVGDVRGVGLFIGVDLIKDE ATRTPATEEAAYLVSRLKENYVLLS TDGPGRNILKFKPPMCFSLDNARQV VAKLDAILTDMEEKVRSCETLRLQP TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase [ Homo sapiens (human) ]
• Official Symbol: PHYKPL
• Synonyms: PHYKPL; 5-phosphohydroxy-L-lysine phospho-lyase; PHLU; AGXT2L2; 5-phosphohydroxy-L-lysine phospho-lyase; 5-phosphonooxy-L-lysine phospho-lyase; alanine--glyoxylate aminotransferase 2-like 2; EC 4.2.3.134
• Gene ID: 85007
• mRNA Refseq: NM_153373
• Protein Refseq: NP_699204
• MIM: 614683
• UniProt ID: Q8IUZ5