Recombinant Human Pim-1 Oncogene, GST-His
Cat.No. : | PIM1-726H |
Product Overview : | Recombinant Human PIM1, Amino acids M1-K313, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9cells. MW = 65,423 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PIM1-726H |
Description : | Pim-1 is a proto-oncogene which encodes for the serine/threonine kinase of the same name. The pim-1 oncogene was first described in relation to murine T-cell lymphomas, as it was the locus most frequently activated by the Moloney murine leukemia virus.[4] Subsequently, the oncogene has been implicated in multiple human cancers, including prostate cancer, acute myeloid leukemia and other hematopoietic malignancies. |
Source : | Baculovirus infected Sf9 cells. |
Purification : | One-step affinity purification using GSH-agarose. |
Product Identity : | PIM1 was confirmed as human PIM1 by mass spectroscopy LC-ESIMS/ MS (Protagen AG, Germany). |
Storage Buffer : | 50 mM Tris-HCl, pH 8.0; 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol. |
Concentration : | 0.185 μg/μl (Bradford method using BSA [Sigma, cat#A-7638, Lot 79H7641] as standard protein). |
Specific Activity : | 273 pmol/μg×min. |
Storage : | -80°C. Avoid repeated freeze-thaw cycles! |
Gene Name : | PIM1 pim-1 oncogene [ Homo sapiens ] |
Synonyms : | PIM1; pim-1 oncogene; PIM; Proto-oncogene serine/threonine-protein kinase Pim-1; EC 2.7.11.1 |
Gene ID : | 5292 |
mRNA Refseq : | NM_002648 |
Protein Refseq : | NP_002639 |
MIM : | 164960 |
UniProt ID : | P11309 |
Chromosome Location : | 6p21 |
Pathway : | Acute myeloid leukemia; Jak-STAT signaling pathway |
Function : | ATP binding; nucleotide binding; transferase activity; manganese ion binding; protein serine/threonine kinase activity; metal ion binding; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
Pim1-4868M | Recombinant Mouse Pim1 Protein, Myc/DDK-tagged | +Inquiry |
PIM1-4125R | Recombinant Rat PIM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIM1-1680H | Recombinant Human PIM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIM1-0920H | Recombinant Human PIM1 Protein (A14-K313), His tagged | +Inquiry |
PIM1-0919H | Recombinant Human PIM1 Protein (A14-K313), Tag Free | +Inquiry |
◆ Lysates | ||
PIM1-3181HCL | Recombinant Human PIM1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1619 | PIM1 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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