Recombinant Human PPARG Protein, MYC/DDK-tagged
Cat.No. : | PPARG-2602H |
Product Overview : | Recombinant Human PPARG protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 57.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PPARG peroxisome proliferator-activated receptor gamma [ Homo sapiens ] |
Official Symbol : | PPARG |
Synonyms : | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma |
Gene ID : | 5468 |
mRNA Refseq : | NM_005037 |
Protein Refseq : | NP_005028 |
MIM : | 601487 |
UniProt ID : | P37231 |
Products Types
◆ Recombinant Protein | ||
PPARG-0778H | Recombinant Human PPARG Protein (P234-Y505), His tagged | +Inquiry |
PPARG-3355R | Recombinant Rhesus Macaque PPARG Protein, His (Fc)-Avi-tagged | +Inquiry |
PPARG-1741H | Recombinant Human PPARG Protein, His (Fc)-Avi-tagged | +Inquiry |
PPARG-0777H | Recombinant Human PPARG Protein (P234-Y505), Tag Free | +Inquiry |
PPARG-547C | Recombinant Cynomolgus Monkey PPARG Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PPARG-492HCL | Recombinant Human PPARG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionPPARG has two isoforms, PPARG1 (57 kDa) and PPARG2, a splice variant with an additional 30 amino acids at the N-terminus.
PPARG has two isoforms with molecular weights of 57 kDa and 54 kDa. Modified PPARG is about 67 kDa.
PPARG stands for Peroxisome Proliferator-Activated Receptor Gamma.
Yes, experimental data suggests a 45 kDa protein immunologically related to PPARG, called mt-PPAR, is located in mitochondria. Its molecular weight is less than PPARG2.
PPARG is a ligand-activated transcription factor that plays a crucial role in regulating lipid homeostasis, adipogenesis, insulin resistance, and organ development.
Defects in PPARG are associated with familial partial lipodystrophy type 3 (FPLD3), susceptibility to obesity, type 2 insulin-resistant diabetes, hypertension, and colon cancer.
PPARG is mainly localized in the nucleus, although it can also be detected in the cytoplasm, exhibiting extra-nuclear/non-genomic actions in certain contexts.
Customer Reviews (3)
Write a reviewIt was reassuring to use a product that adhered to green chemistry principles, reducing our impact on the environment.
The company's dedication to environmental sustainability reflected positively on the product and our research initiatives.
We appreciated the option to request modifications or custom formulations to meet our project's requirements.
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