Recombinant Human PPM1G Protein, GST-tagged

• Cat.No.: PPM1G-001H
• Product Overview: Recombinant full-length human PP2Cgamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: ~105 kDa
• Applications: Phosphatase Assay; Western Blot
• Stability: One year at -70 centigrade form date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Storage Buffer: Recombinant protein stored in 20mM MOPS, pH7.5, 300mM NaCl, 10mM glitathione, 0.25mM DTT, 0.1mM PMSF, 0.25% glycerol.

Gene Information

• Gene Name: PPM1G protein phosphatase, Mg2+/Mn2+ dependent 1G [ Homo sapiens (human) ]
• Official Symbol: PPM1G
• Synonyms: PPM1G; protein phosphatase, Mg2+/Mn2+ dependent 1G; PP2CG; PPP2CG; PP2CGAMMA; protein phosphatase 1G; PP2C-gamma; protein phosphatase 1C; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform
  protein phosphatase 2C gamma isoform; protein phosphatase 2C isoform gamma; protein phosphatase magnesium-dependent 1 gamma; EC 3.1.3.16
• Gene ID: 5496
• mRNA Refseq: NM_177983
• Protein Refseq: NP_817092
• MIM: 605119
• UniProt ID: O15355