Recombinant Human PPP1R8 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PPP1R8 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PPP1R8-1897H
Product Overview : PPP1R8 MS Standard C13 and N15-labeled recombinant protein (NP_612568) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 38.5 kDa
AA Sequence : MAAAANSGSS LPLFDCPTWA GKPPPGLHLD VVKGDKLIEK LIIDEKKYYL FGRNPDLCDF TIDHQSCSRV HAALVYHKHL KRVFLIDLNS THGTFLGHIR LEPHKPQQIP IDSTVSFGAS TRAYTLREKP QTLPSAVKGD EKMGGEDDEL KGLLGLPEEE TELDNLTEFI TAHNKRISTL TIEEGNLDIQ RPKRKRKNSR VTFSEDDEII NPEDVDPSVG RFRNMVQTAV VPVKKKRVEG PGSLGLEESG SRRMQNFAFS GGLYGGLPPT HSEAGSQPHG IHGTALIGGL PMPYPNLAPD VDLTPVVPSA VNMNPAPNPA VYNPEAVNEP KKKKYAKEAW PGKKPTPSLL ITRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PPP1R8 protein phosphatase 1 regulatory subunit 8 [ Homo sapiens (human) ]
Official Symbol : PPP1R8
Synonyms : PPP1R8; protein phosphatase 1, regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; nuclear inhibitor of protein phosphatase 1; activator of RNA decay; ard 1; ARD1; NIPP 1; NIPP1; nuclear subunit of PP 1; PRO2047; protein phosphatase 1 regulatory subunit 8; RNase E; nuclear subunit of PP-1; nuclear inhibitor of protein phosphatase-1; ARD-1; NIPP-1;
Gene ID : 5511
mRNA Refseq : NM_138558
Protein Refseq : NP_612568
MIM : 602636
UniProt ID : Q12972

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