Recombinant Human PRC1 Protein, His-tagged

• Cat.No.: PRC1-527H
• Product Overview: Recombinant Human PRC1 Protein(NP_003972.1) (Met 1-Ser 620) was expressed in Insect Cells, with a polyhistidine tag at the N-terminus.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 1-620 aa
• Form: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 20% gly, 3mM DTT.
• Molecular Mass: The recombinant human PRC1 consists of 639 amino acids and predicts a molecular mass of 74 kDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE.
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Publications:
  • BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway (2025)

Gene Information

• Gene Name: PRC1 protein regulator of cytokinesis 1 [ Homo sapiens ]
• Official Symbol: PRC1
• Synonyms: PRC1; protein regulator of cytokinesis 1; anaphase spindle elongation 1 homolog (S. cerevisiae); ASE1; protein regulating cytokinesis 1; anaphase spindle elongation 1 homolog; MGC1671; MGC3669
• Gene ID: 9055
• mRNA Refseq: NM_003981
• Protein Refseq: NP_003972
• MIM: 603484
• UniProt ID: O43663