Recombinant Human PRDX2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PRDX2-697H |
Product Overview : | PRDX2 MS Standard C13 and N15-labeled recombinant protein (NP_859428) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 15.6 kDa |
AA Sequence : | MASGNARIGKPAPDFKATAVVDGAF KEVKLSDYKGKYVVLFFYPLDFTFV CPTEIIAFSNRAEDFRKLGCEVLGV SVDSQFTHLAWYEQGPKREVAAKLT PSGPSSVASWPLLNLWNLRFPIVKI METLPPKSLRMMTVISITRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | PRDX2 peroxiredoxin 2 [ Homo sapiens (human) ] |
Official Symbol : | PRDX2 |
Synonyms : | PRDX2; peroxiredoxin 2; TDPX1; peroxiredoxin-2; MGC4104; natural killer enhancing factor B; NKEFB; PRP; PRX2; PRXII; thiol specific antioxidant 1; thioredoxin peroxidase 1; thioredoxin dependent peroxide reductase 1; torin; TSA; NKEF-B; thiol-specific antioxidant 1; thiol-specific antioxidant protein; natural killer cell-enhancing factor B; thioredoxin-dependent peroxide reductase 1; TPX1; |
Gene ID : | 7001 |
mRNA Refseq : | NM_181738 |
Protein Refseq : | NP_859428 |
MIM : | 600538 |
UniProt ID : | P32119 |
Products Types
◆ Recombinant Protein | ||
PRDX2-1758H | Recombinant Human PRDX2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRDX2-2910H | Recombinant Human PRDX2 Protein, MYC/DDK-tagged | +Inquiry |
PRDX2-870M | Recombinant Mouse PRDX2 Protein (Met1-Asn198), His-tagged | +Inquiry |
PRDX2-332H | Recombinant Human PRDX2 Protein, His-tagged | +Inquiry |
Prdx2-334H | Recombinant Mouse Prdx2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRDX2-564HCL | Recombinant Human PRDX2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPRDX2's role in maintaining cellular redox balance implicates it in cancer progression. Modulating PRDX2 levels may offer avenues for developing novel cancer therapies.
As with any targeted therapy, potential side effects need thorough investigation. Modulating PRDX2 levels could impact normal cellular functions, and careful assessment is required.
Some studies suggest that PRDX2 levels may have prognostic value in diseases associated with oxidative stress, providing insights into disease progression.
Yes, PRDX2 is a potential drug target, but challenges include developing specific modulators and understanding the protein's complex regulatory mechanisms.
Research suggests that altered levels of PRDX2 could serve as a biomarker in diseases associated with oxidative stress, offering potential diagnostic applications.
Customer Reviews (3)
Write a reviewI am eager to embark on this scientific journey, empowered by the high-quality PRDX2 protein and the manufacturer's unparalleled assistance.
The manufacturer's prompt and reliable technical support serves as an invaluable resource, reinforcing my confidence in the PRDX2 protein's effectiveness and enabling smooth progress in my experiments.
Its remarkable purity and functional attributes make it an optimal choice for my research, ensuring accurate and reliable outcomes.
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