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Recombinant Human PRMT5 Protein, His (Fc)-Avi-tagged

Cat.No. : PRMT5-1771H
Product Overview : Recombinant Human PRMT5 with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Human
Tag : His&Fc&Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : PRMT5 protein arginine methyltransferase 5 [ Homo sapiens (human) ]
Official Symbol : PRMT5
Synonyms : HSL7; JBP1; SKB1; IBP72; SKB1Hs; HRMT1L5
Gene ID : 10419
mRNA Refseq : NM_006109.5
Protein Refseq : NP_006100.2
MIM : 604045
UniProt ID : O14744

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
02/18/2023

    Great performance in ELISA.

    11/01/2018

      Its purity and functionality ensure precise and reproducible results, enabling me to achieve my research objectives with confidence.

      10/30/2016

        The PRMT5 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

        Q&As (5)

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        Are there any ongoing clinical trials targeting PRMT5? 05/31/2021

        Yes, there are ongoing clinical trials investigating the efficacy of PRMT5 inhibitors in various cancer types.

        How does PRMT5 affect cellular differentiation? 12/10/2019

        PRMT5 influences cellular differentiation by regulating the expression of genes involved in the process.

        Can PRMT5 inhibitors be used in combination therapies? 07/05/2018

        Yes, there is interest in exploring combination therapies involving PRMT5 inhibitors with other anticancer agents to enhance treatment efficacy.

        How does PRMT5 contribute to epigenetic regulation? 04/26/2016

        PRMT5 methylates histone proteins, leading to changes in chromatin structure and gene expression, thus playing a crucial role in epigenetic regulation.

        How does PRMT5 influence neurodegenerative diseases? 01/04/2016

        PRMT5 has been implicated in neurodegenerative diseases, and understanding its role may provide insights into developing therapies for conditions like Alzheimer's and Parkinson's disease.

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