Recombinant Human PSG1, His-tagged

• Cat.No.: PSG1-189H
• Product Overview: PSG1, 35-419aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 35-419aa
• Description: PSG1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences. PSGs are part of the carcinoembryonic antigen (CEA) family and serve as early biochemical markers of syncytiotrophoblast formation. The sequence specificity of DNA binding is conferred by Zn (II) fingers, whereas a different region of PSG1 appears to regulate the affinity of DNA binding. Additionally, PSG1 is believed to mediate placental vascular morphogenesis by enhancing VEGF-A production and endothelial tube formation. Recombinant human PSG1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 45.9kDa (408aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQVTIEAE PTKVSEGKDV LLLVHNLPQN LTGYIWYKGQ MRDLYHYITS YVVDGEIIIY GPAYSGRETA YSNASLLIQN VTREDAGSYT LHIIKGDDGT RGVTGRFTFT LHLETPKPSI SSSNLNPRET MEAVSLTCDP ETPDASYLWW MNGQSLPMTH SLKLSETNRT LFLLGVTKYT AGPYECEIRN PVSASRSDPV TLNLLPKLPK PYITINNLNP RENKDVLNFT CEPKSENYTY IWWLNGQSLP VSPRVKRPIE NRILILPSVT RNETGPYQCE IRDRYGGIRS DPVTLNVLYG PDLPRIYPSF TYYRSGEVLY LSCSADSNPP AQYSWTINEK FQLPGQKLFI RHITTKHSGL YVCSVRNSAT GKESSKSMTV EVSGKWIP
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PSG1 pregnancy specific beta-1-glycoprotein 1 [ Homo sapiens ]
• Official Symbol: PSG1
• Synonyms: PSG1; pregnancy specific beta-1-glycoprotein 1; PSBG1; pregnancy-specific beta-1-glycoprotein 1; CD66f; PBG1; PSGGA; PSG95; PSBG-1; FL-NCA-1/2; PS-beta-C/D; PS-beta-G-1; CD66 antigen-like family member F; pregnancy-specific glycoprotein 1; pregnancy-specific B-1 glycoprotein; pregnancy-specific beta-1 glycoprotein C/D; fetal liver non-specific cross-reactive antigen 1/2; SP1; B1G1; DHFRP2; PSGIIA; FLJ90598; FLJ90654
• Gene ID: 5669
• mRNA Refseq: NM_006905
• Protein Refseq: NP_008836
• MIM: 176390
• UniProt ID: P11464
• Chromosome Location: 19q13.2