Recombinant Human PTPRE Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PTPRE Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PTPRE-3685H
Product Overview : PTPRE MS Standard C13 and N15-labeled recombinant protein (NP_569119) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 74.4 kDa
AA Sequence : MSNRSSFSRL TWFRKQRKAV VSTSDKKMPN GILEEQEQQR VMLLSRSPSG PKKYFPIPVE HLEEEIRIRS ADDCKQFREE FNSLPSGHIQ GTFELANKEE NREKNRYPNI LPNDHSRVIL SQLDGIPCSD YINASYIDGY KEKNKFIAAQ GPKQETVNDF WRMVWEQKSA TIVMLTNLKE RKEEKCHQYW PDQGCWTYGN IRVCVEDCVV LVDYTIRKFC IQPQLPDGCK APRLVSQLHF TSWPDFGVPF TPIGMLKFLK KVKTLNPVHA GPIVVHCSAG VGRTGTFIVI DAMMAMMHAE QKVDVFEFVS RIRNQRPQMV QTDMQYTFIY QALLEYYLYG DTELDVSSLE KHLQTMHGTT THFDKIGLEE EFRKLTNVRI MKENMRTGNL PANMKKARVI QIIPYDFNRV ILSMKRGQEY TDYINASFID GYRQKDYFIA TQGPLAHTVE DFWRMIWEWK SHTIVMLTEV QEREQDKCYQ YWPTEGSVTH GEITIEIKND TLSEAISIRD FLVTLNQPQA RQEEQVRVVR QFHFHGWPEI GIPAEGKGMI DLIAAVQKQQ QQTGNHPITV HCSAGAGRTG TFIALSNILE RVKAEGLLDV FQAVKSLRLQ RPHMVQTLEQ YEFCYKVVQD FIDIFSDYAN FKTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PTPRE protein tyrosine phosphatase receptor type E [ Homo sapiens (human) ]
Official Symbol : PTPRE
Synonyms : PTPRE; protein tyrosine phosphatase, receptor type, E; receptor-type tyrosine-protein phosphatase epsilon; PTPE; protein tyrosine phosphatase, receptor type, epsilon polypeptide; HPTPE; FLJ57799; FLJ58245; R-PTP-EPSILON; DKFZp313F1310;
Gene ID : 5791
mRNA Refseq : NM_130435
Protein Refseq : NP_569119
MIM : 600926
UniProt ID : P23469

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