Recombinant Human RAB21 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RAB21-3903H
• Product Overview: RAB21 MS Standard C13 and N15-labeled recombinant protein (NP_055814) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 24.3 kDa
• AA Sequence: MAAAGGGGGGAAAAGRAYSFKVVLL GEGCVGKTSLVLRYCENKFNDKHIT TLQASFLTKKLNIGGKRVNLAIWDT AGQERFHALGPIYYRDSNGAILVYD ITDEDSFQKVKNWVKELRKMLGNEI CLCIVGNKIDLEKERHVSIQEAESY AESVGAKHYHTSAKQNKGIEELFLD LCKRMIETAQVDERAKGNGSSQPGT ARRGVQIIDDEPQAQTSGGGCCSSG TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RAB21 RAB21, member RAS oncogene family [ Homo sapiens (human) ]
• Official Symbol: RAB21
• Synonyms: RAB21; RAB21, member RAS oncogene family; ras-related protein Rab-21; KIAA0118
• Gene ID: 23011
• mRNA Refseq: NM_014999
• Protein Refseq: NP_055814
• MIM: 612398
• UniProt ID: Q9UL25