Recombinant Human RCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | RCC1-2204H |
| Product Overview : | SNHG3 MS Standard C13 and N15-labeled recombinant protein (NP_001041664) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 45 kDa |
| AA Sequence : | MSPKRIAKRR SPPADAIPKS KKVKVSHRSH STEPGLVLTL GQGDVGQLGL GENVMERKKP ALVSIPEDVV QAEAGGMHTV CLSKSGQVYS FGCNDEGALG RDTSVEGSEM VPGKVELQEK VVQVSAGDSH TAALTDDGRV FLWGSFRDNN GVIGLLEPMK KSMVPVQVQL DVPVVKVASG NDHLVMLTAD GDLYTLGCGE QGQLGRVPEL FANRGGRQGL ERLLVPKCVM LKSRGSRGHV RFQDAFCGAY FTFAISHEGH VYGFGLSNYH QLGTPGTESC FIPQNLTSFK NSTKSWVGFS GGQHHTVCMD SEGKAYSLGR AEYGRLGLGE GAEEKSIPTL ISRLPAVSSV ACGASVGYAV TKDGRVFAWG MGTNYQLGTG QDEDAWSPVE MMGKQLENRV VLSVSSGGQH TVLLVKDKEQ STRTRPLEQK LISEEDLAAN DILDYKDDDD KV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | RCC1 regulator of chromosome condensation 1 [ Homo sapiens (human) ] |
| Official Symbol : | RCC1 |
| Synonyms : | RCC1; regulator of chromosome condensation 1; CHC1, chromosome condensation 1; regulator of chromosome condensation; cell cycle regulatory protein; SNHG3-RCC1 readthrough transcript; guanine nucleotide-releasing protein; CHC1; RCC1-I; SNHG3-RCC1; |
| Gene ID : | 1104 |
| mRNA Refseq : | NM_001048199 |
| Protein Refseq : | NP_001041664 |
| MIM : | 179710 |
| UniProt ID : | P18754 |
◆ Recombinant Protein
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| RCC1-1326H | Recombinant Human RCC1 Protein, GST-Tagged | +Inquiry |
| RCC1-181H | Recombinant Human RCC1 Protein, Strep-tagged | +Inquiry |
| RCC1-2229H | Recombinant Human RCC1, GST-tagged | +Inquiry |
| RCC1-01H | Recombinant Human RCC1 protein, His-tagged | +Inquiry |
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◆ Native Protein
| RCC1-31302TH | Native Human RCC1 | +Inquiry |
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◆ Lysates
| RCC1-2445HCL | Recombinant Human RCC1 293 Cell Lysate | +Inquiry |
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