Recombinant Human ROR1

Cat.No. : ROR1-30958TH
Product Overview : Recombinant fragment of Human ROR1 with a N terminal proprietary tag. Predicted molecular weight 36.63 kDa.
  • Specification
  • Gene Information
  • Related Products
  • Download
Description : The protein encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : ANCIRIGIPMADPINKNHKCYNSTG VDYRGTVSVTKSGRQCQPWNSQYPH THTFTALRFPELNGGHSYCRNPGNQ KEAPWCFTLDENFKSDLCDIPACGK
Sequence Similarities : Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.Contains 1 FZ (frizzled) domain.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 kringle domain.Contains 1 protein kinase domain.
Gene Name : ROR1 receptor tyrosine kinase-like orphan receptor 1 [ Homo sapiens ]
Official Symbol : ROR1
Synonyms : ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1;
Gene ID : 4919
mRNA Refseq : NM_001083592
Protein Refseq : NP_001077061
MIM : 602336
Uniprot ID : Q01973
Chromosome Location : 1p32-p31
Pathway : Nuclear Receptors, organism-specific biosystem;
Function : ATP binding; Wnt-protein binding; kinase activity; nucleotide binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (4)

Ask a question
What is the expression level of ROR1 in normal tissues. 11/28/2022

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression? 07/14/2022

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in? 12/26/2021

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in? 03/01/2021

ROR1 is involved in the study of breast, lung and ovarian cancers.

Customer Reviews (3)

Write a review
Reviews
10/18/2022

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    08/13/2022

      Excellent after-sales service, solving many experimental problems.

      04/12/2021

        Fast and timely shipment helped me to get satisfactory experimental results in short time.

        Ask a Question for All ROR1 Products

        Required fields are marked with *

        My Review for All ROR1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends