| Description : |
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
27.6 kDa |
| Protein Length : |
263 |
| AA Sequence : |
MRLGLCVVALVLSWTHLTISSRGIK GKRQRRISAEGSQACAKGCELCSEV NGCLKCSPKLFILLERNDIRQVGVC LPSCPPGYFDARNPDMNKCIKCKIE HCEACFSHNFCTKCKEGLYLHKGRC YPACPEGSSAANGTMECSSPAQCEM SEWSPWGPCSKKQQLCGFRRGSEER TRRVLHAPVGDHAACSDTKETRRCT VRRVPCPEGQKRRKGGQGRRENANR NLARKESKEAGAGSRRRKGQQQQQQ QGTVGPLTSAGPA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
