Recombinant Human RSPO3 Protein

• Cat.No.: RSPO3-35H
• Product Overview: Recombinant human R-spondin 3 protein without tag was expressed in E. coli.
  Animal-free (AOF) and carrier protein-free.
  Mass spectrometry: single species with expected mass.
  Analytical reversed-phase: single sharp peak.
  Recovery from stock vial: >95%

Specification

• Description: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.
• Source: E. coli
• Species: Human
• Molecular Mass: 17 kDa
• Endotoxin: <0.005 EU/μg protein (below level of detection)
• Applications: Intestinal organoid culture
• Storage: Resuspend in 10mM HCl at >100 μg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade
• Storage Buffer: Lyophilized from acetonitrile, TFA

Gene Information

• Gene Name: RSPO3 R-spondin 3 [ Homo sapiens (human) ]
• Official Symbol: RSPO3
• Synonyms: RSPO3; R-spondin 3; PWTSR; THSD2; CRISTIN1
• Gene ID: 84870
• mRNA Refseq: NM_032784
• Protein Refseq: NP_116173
• MIM: 610574
• UniProt ID: Q9BXY4