Recombinant Human RUSC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RUSC1-872H
• Product Overview: RUSC1 MS Standard C13 and N15-labeled recombinant protein (NP_055143) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF-dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.6 kDa
• AA Sequence: MAEAQSGTGQLQEQKKGLLIAVSVS VDKIISHFGAARNLVQKAQLGDSRL SPDVGHLVLTTLCPALHALVADGLK PFRKDLITGQRRSSPWSVVEASVKP GSSTRSLGTLYSQVSRLAPLSSSRS RFHAFILGLLNTKQLELWFSSLQED AGLLSLLYLPTGFFSLARGGCPSLS TELLLLLQPLSVLTFHLDLLFEHHH HLPLGPPQAPAPPGPPPALQQTMQA MLHFGGRLAQSLRGTSKEAASDPSD SPNLPTPGSWWEQLTQASRVYASGG TEGFPLSRWAPGRHGTAAEEGAQER PLPTDEMAPGRGLWLGRLFGVPGGP AENENGALKSRRPSSWLPPTVSVLA LVKRGAPPEMPSPQELEASAPRMVQ THRAVRALCDHTAARPDQLSFRRGE VLRVITTVDEDWLRCGRDGMEGLVP VGYTSLVLTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RUSC1 RUN and SH3 domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: RUSC1
• Synonyms: RUSC1; RUN and SH3 domain containing 1; RUN and SH3 domain-containing protein 1; NESCA; new molecule containing SH3 at the carboxy-terminus; DKFZp761A1822
• Gene ID: 23623
• mRNA Refseq: NM_014328
• Protein Refseq: NP_055143
• MIM: 617318
• UniProt ID: Q9BVN2