Recombinant Human SEC24B Protein, MYC/DDK-tagged

• Cat.No.: SEC24B-602H
• Product Overview: Recombinant human SEC24B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 133.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SEC24 homolog B, COPII coat complex component[ Homo sapiens ]
• Official Symbol: SEC24B
• Synonyms: SEC24; SEC24
• Gene ID: 10427
• mRNA Refseq: NM_001042734.1
• Protein Refseq: NP_001036199.1
• MIM: 607184
• UniProt ID: O95487