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Recombinant Human SH2B3 Mutant (R262W) Protein, Myc/DDK-tagged

Cat.No. : SH2B3-051H
Product Overview : Purified mutant recombinant protein of Human SH2B adaptor protein 3 (SH2B3), mutation at (R262W) with a Myc/DDK tag was expressed in HEK293
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Description : This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 63 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : > 50 μg/mL as determined by microplate Bradford method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Gene Name : SH2B3 SH2B adaptor protein 3 [ Homo sapiens (human) ]
Official Symbol : SH2B3
Synonyms : SH2B3; SH2B adaptor protein 3; LNK; IDDM20; SH2B adapter protein 3; lymphocyte-specific adapter protein Lnk; signal transduction protein Lnk; truncated SH2B3
Gene ID : 10019
mRNA Refseq : NM_005475
Protein Refseq : NP_005466
MIM : 605093
UniProt ID : Q9UQQ2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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