Recombinant Human SLAMF7 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : SLAMF7-2499H
Product Overview : SLAMF7 MS Standard C13 and N15-labeled recombinant protein (NP_067004) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Isoform 3 does not mediate any NK cell activation.
Source : HEK293
Species : Human
Tag : Myc&DDK
Molecular Mass : 37.2 kDa
AA Sequence : MAGSPTCLTLIYILWQLTGSAASGP VKELVGSVGGAVTFPLKSKVKQVDS IVWTFNTTPLVTIQPEGGTIIVTQN RNRERVDFPDGGYSLKLSKLKKNDS GIYYVGIYSSSLQQPSTQEYVLHVY EHLSKPKVTMGLQSNKNGTCVTNLT CCMEHGEEDVIYTWKALGQAANESH NGSILPISWRWGESDMTFICVARNP VSRNFSSPILARKLCEGAADDPDSS MVLLCLLLVPLLLSLFVLGLFLWFL KRERQEEYIEEKKRVDICRETPNIC PHSGENTEYDTIPHTNRTILKEDPA NTVYSTVEIPKKMENPHSLLTMPDT PRLFAYENVITRTRPLEQKLISEED LAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : SLAMF7 SLAM family member 7 [ Homo sapiens (human) ]
Official Symbol : SLAMF7
Synonyms : SLAMF7; SLAM family member 7; 19A; CD319; CRACC; CS1; protein 19A; CD2 subset 1; 19A24 protein; membrane protein FOAP-12; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; novel LY9 (lymphocyte antigen 9) like protein;
Gene ID : 57823
mRNA Refseq : NM_021181
Protein Refseq : NP_067004
MIM : 606625
UniProt ID : Q9NQ25

Not For Human Consumption!

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Customer Reviews (3)

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07/28/2023

    It has a high solubility and can be easily prepared at the desired concentration.

    07/26/2021

      It was found to be well active and could effectively perform the required biological activity experiments.

      04/15/2020

        It was observed that SLAMF7 had good crystallinity, which was conducive to crystallography research.

        Q&As (6)

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        What is the mechanism by which SLAMF7 protein regulates immune responses? 10/13/2022

        SLAMF7 protein is involved in regulating immune cell activation, proliferation, and transmission of background signals by binding to activating ligands, such as CD319, thereby influencing the immune response.

        What is the potential of combining SLAMF7 protein with immunotherapy? 05/02/2022

        By combining with immunotherapy, such as anti-PD-1 antibodies, the immune response can be further enhanced and the anti-tumor effect can be improved. The study of SLAMF7 protein provides a new direction for the development of combinatorial therapeutic strategies.

        In which tissues or cells is SLAMF7 protein expressed? 12/13/2021

        This protein is mainly expressed in the immune system, including immune cells such as plasma cells, NK cells, and activated T cells.

        Does the SLAMF7 protein have a similar role in other types of cancer? 11/14/2020

        The role of SLAMF7 protein in other types of cancer is unclear, and further research is needed to determine its potential role in other cancers.

        Does SLAMF7 protein have potential in the treatment of multiple myeloma? 05/20/2020

        Yes, the SLAMF7 protein has been shown to be a potential therapeutic target. A monoclonal antibody drug targeting SLAMF7 protein (Elotuzumab) has been developed for the treatment of multiple myeloma.

        What is the function of SLAMF7 protein in multiple myeloma? 12/11/2019

        SLAMF7 protein interacts with NK cells in multiple myeloma and plays a role in inhibiting and controlling tumor growth by activating the anti-tumor activity of NK cells.

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