Recombinant Human SLAMF7 Protein (Ser23-Met226), C-hFc and 6×His-tagged

• Cat.No.: SLAMF7-570H
• Product Overview: Recombinant Human SLAMF7 Protein (Ser23-Met226) with C-hFc and 6×His tag was expressed in HEK293.

Specification

• Description: SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
• Source: HEK293
• Species: Human
• Tag: C-hFc and 6×His
• Form: Lyophilized
• Molecular Mass: 70 kDa
• Protein Length: Ser23-Met226
• Purity: > 95% as determined by SDS-PAGE and Coomassie blue staining.
• Storage: Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing)
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 9 % trehalose is added as protectants before lyophilization.

Gene Information

• Gene Name: SLAMF7 SLAM family member 7 [ Homo sapiens (human) ]
• Official Symbol: SLAMF7
• Synonyms: SLAMF7; SLAM family member 7; 19A; CS1; CD319; CRACC; SLAM family member 7; 19A24 protein; CD2 subset 1; CD2-like receptor activating cytotoxic cells; membrane protein FOAP-12; novel LY9 (lymphocyte antigen 9) like protein; protein 19A
• Gene ID: 57823
• mRNA Refseq: NM_021181
• Protein Refseq: NP_067004
• MIM: 606625
• UniProt ID: A8K3U1