Recombinant Human SMAD family member 5 Protein, His tagged

• Cat.No.: SMAD5-001H
• Product Overview: Recombinant Human SMAD5 Protein (155-258aa) with His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: C-His
• Protein length: 155-258aa
• Molecular Mass: 12 kDa
• AA Sequence: MVQFRNLSHNEPHMPQNATFPDSFH QPNNTPFPLSPNSPYPPSPASSTYP NSPASSGPGSPFQLPADTPPPAYMP PDDQMGQDNSQPMDTSNNMIPQIMP SISSRHHHHHHHH
• Endotoxin: < 1 EU/μg by LAL
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH7.4
• Concentration: 1 mg/mL by BCA

Gene Information

• Gene Name: SMAD5 SMAD family member 5 [ Homo sapiens (human) ]
• Official Symbol: SMAD5
• Synonyms: SMAD5; SMAD family member 5; MAD, mothers against decapentaplegic homolog 5 (Drosophila) , MADH5, SMAD, mothers against DPP homolog 5 (Drosophila); mothers against decapentaplegic homolog 5; Dwfc; JV5 1; SMA- and MAD-related protein 5; SMAD, mothers against DPP homolog 5; MAD, mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; DWFC; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323
• Gene ID: 4090
• mRNA Refseq: NM_001001419
• Protein Refseq: NP_001001419
• MIM: 603110
• UniProt ID: Q99717