Recombinant Human SOD1 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | SOD1-070H |
Product Overview : | SOD1 MS Standard C13 and N15-labeled recombinant protein (NP_000445) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 15.9 kDa |
AA Sequence : | MATKAVCVLKGDGPVQGIINFEQKE SNGPVKVWGSIKGLTEGLHGFHVHE FGDNTAGCTSAGPHFNPLSRKHGGP KDEERHVGDLGNVTADKDGVADVSI EDSVISLSGDHCIIGRTLVVHEKAD DLGKGGNEESTKTGNAGSRLACGVI GIAQTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | SOD1 superoxide dismutase 1 [ Homo sapiens (human) ] |
Official Symbol : | SOD1 |
Synonyms : | SOD1; superoxide dismutase 1; ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD; superoxide dismutase [Cu-Zn]; Cu/Zn superoxide dismutase; SOD, soluble; epididymis secretory protein Li 44; indophenoloxidase A; superoxide dismutase 1, soluble; superoxide dismutase, cystolic; EC 1.15.1.1 |
Gene ID : | 6647 |
mRNA Refseq : | NM_000454 |
Protein Refseq : | NP_000445 |
MIM : | 147450 |
UniProt ID : | P00441 |
Products Types
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SOD1-2069H | Recombinant Human SOD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
SOD1-102B | Active Native Bovine SOD, modified | +Inquiry |
CED026 | Active Bovine Superoxide Dismutase (SOD), High Purity >95% | +Inquiry |
SOD1-101B | Active Native Bovine SOD | +Inquiry |
◆ Lysates | ||
SOD1-1576HCL | Recombinant Human SOD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTherapeutic strategies may involve modulating SOD1 activity or expression to mitigate oxidative stress-related damage.
SOD1 acts as an antioxidant, converting superoxide radicals to hydrogen peroxide and oxygen.
Mutations in SOD1 can result in loss or gain of function, contributing to disease development.
SOD1 mutations are implicated in Amyotrophic Lateral Sclerosis (ALS), leading to neurodegeneration.
SOD1 is primarily located in the cytoplasm and mitochondrial intermembrane space.
It helps maintain cellular redox balance, protecting cells from oxidative damage.
It plays a crucial role in cellular defense against oxidative stress.
Customer Reviews (3)
Write a reviewWorked perfectly, no problems.
Quick delivery, fantastic product.
Reliable results every time.
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