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Recombinant Human SOD1 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : SOD1-070H
Product Overview : SOD1 MS Standard C13 and N15-labeled recombinant protein (NP_000445) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 15.9 kDa
AA Sequence : MATKAVCVLKGDGPVQGIINFEQKE SNGPVKVWGSIKGLTEGLHGFHVHE FGDNTAGCTSAGPHFNPLSRKHGGP KDEERHVGDLGNVTADKDGVADVSI EDSVISLSGDHCIIGRTLVVHEKAD DLGKGGNEESTKTGNAGSRLACGVI GIAQTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : SOD1 superoxide dismutase 1 [ Homo sapiens (human) ]
Official Symbol : SOD1
Synonyms : SOD1; superoxide dismutase 1; ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD; superoxide dismutase [Cu-Zn]; Cu/Zn superoxide dismutase; SOD, soluble; epididymis secretory protein Li 44; indophenoloxidase A; superoxide dismutase 1, soluble; superoxide dismutase, cystolic; EC 1.15.1.1
Gene ID : 6647
mRNA Refseq : NM_000454
Protein Refseq : NP_000445
MIM : 147450
UniProt ID : P00441

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there potential therapeutic strategies targeting SOD1 for disease treatment? 01/23/2022

Therapeutic strategies may involve modulating SOD1 activity or expression to mitigate oxidative stress-related damage.

What is the primary biological function of SOD1 in cells? 01/03/2022

SOD1 acts as an antioxidant, converting superoxide radicals to hydrogen peroxide and oxygen.

What are the genetic implications of mutations in the SOD1 gene? 03/01/2021

Mutations in SOD1 can result in loss or gain of function, contributing to disease development.

How is SOD1 implicated in neurodegenerative diseases? 02/09/2020

SOD1 mutations are implicated in Amyotrophic Lateral Sclerosis (ALS), leading to neurodegeneration.

In which cellular compartments is SOD1 primarily located? 11/14/2019

SOD1 is primarily located in the cytoplasm and mitochondrial intermembrane space.

What role does SOD1 play in maintaining cellular redox balance? 08/27/2019

It helps maintain cellular redox balance, protecting cells from oxidative damage.

How does SOD1 contribute to the cellular antioxidant defense system? 02/27/2019

It plays a crucial role in cellular defense against oxidative stress.

Customer Reviews (3)

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Reviews
11/15/2022

    Worked perfectly, no problems.

    10/09/2020

      Quick delivery, fantastic product.

      10/02/2020

        Reliable results every time.

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