Recombinant Human SOST protein, His-Avi-tagged SOST-471H

Recombinant Human SOST protein, His-Avi-tagged

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Cat.No. :	SOST-471H
Product Overview :	Human SOST/Sclerostin Protein is expressed from mammalian with a Poly-His and Avi Tag at the N-terminal. It contains Gln 24 - Tyr 213.
Description :	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Source :	HEK293
Species :	Human
Tag :	His-Avi
Form :	Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass :	The Human SOST/Sclerostin Protein has a calculated MW of 24.2kDa. As a result of glycosylation, the protein migrates as 25-40 kDa under reducing (R) condition (Bis-Tris PAGE).
Protein length :	It contains Gln 24 - Tyr 213.
Endotoxin :	Less than 0.1 EU per ug by the LAL method.
Purity :	> 95% as determined by Bis-Tris PAGE
Storage :	The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution :	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :
ELISA data :

Gene Name :	SOST sclerostin [ Homo sapiens ]
Official Symbol :	SOST
Synonyms :	sclerostin; SOST; VBCHsclerosteosis
Gene ID :	50964
mRNA Refseq :	NM_025237
Protein Refseq :	NP_079513
MIM :	605740
UniProt ID :	Q9BQB4