Recombinant Human SOST protein, His-Avi-tagged


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Recombinant Human SOST protein, His-Avi-tagged

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Cat.No. : SOST-471H
Product Overview : Human SOST/Sclerostin Protein is expressed from mammalian with a Poly-His and Avi Tag at the N-terminal. It contains Gln 24 - Tyr 213.
Description : SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Source : HEK293
Species : Human
Tag : His-Avi
Form : Supplied as 0.22um filtered solution in PBS (pH 7.4).
Molecular Mass : The Human SOST/Sclerostin Protein has a calculated MW of 24.2kDa. As a result of glycosylation, the protein migrates as 25-40 kDa under reducing (R) condition (Bis-Tris PAGE).
Protein length : It contains Gln 24 - Tyr 213.
Endotoxin : Less than 0.1 EU per ug by the LAL method.
Purity : > 95% as determined by Bis-Tris PAGE
Storage : The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Tris-Bis PAGE :

ELISA data :

Gene Name : SOST sclerostin [ Homo sapiens ]
Official Symbol : SOST
Synonyms : sclerostin; SOST; VBCHsclerosteosis
Gene ID : 50964
mRNA Refseq : NM_025237
Protein Refseq : NP_079513
MIM : 605740
UniProt ID : Q9BQB4

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