Recombinant Human SP1 Protein, His-tagged

• Cat.No.: SP1-113H
• Product Overview: Recombinant Human SP1 Protein, fused to His-tag, was expressed in E.coli.

Specification

• Description: The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in 30mM Tris, 300mM NaCl, pH8.0.
• Molecular Mass: ~18.9 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRAHLRWHTGERPFMCTW SYCGKRFTRS DELQRHKRTH TGEKKFACPE CPKRFMRSDHLSKHIKTHQN KKGGPGVALS VGTLPLDSGA GSEGSGTATP SALITTNMVA MEAICPEGIA RLANSGINVM QVADLQSILEHHHHH
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.17 mg/ml

Gene Information

• Gene Name: SP1 Sp1 transcription factor [ Homo sapiens (human) ]
• Official Symbol: SP1
• Gene ID: 6667
• mRNA Refseq: NM_001251825
• Protein Refseq: NP_001238754
• MIM: 189906
• UniProt ID: P08047