Recombinant Human SPARC protein, MBP-tagged
Cat.No. : | SPARC-34H |
Product Overview : | Recombinant Human SPARC protein fused with MBP, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | MBP |
Form : | 20mM Tris-HCl, 0.2M NaCl, 1mM EDTA, 10mM Maltose, pH 7.4. No preservatives added. |
Molecular Mass : | 79298,5 Da |
Protein length : | 1-303 aa (full-length) |
Purity : | >90 % as determined by SDS-PAGE analysis |
Applications : | ELISA, WB, Antibody Production, Protein array. |
Storage : | Frozen / Solution. For extended storage, conserve at −80ºC. Repeated freezing and thawing is not recommended. Store working aliquots at 4ºC for up to one week. |
Gene Name : | SPARC secreted protein, acidic, cysteine-rich (osteonectin) [ Homo sapiens ] |
Official Symbol : | SPARC |
Synonyms : | SPARC; secreted protein, acidic, cysteine-rich (osteonectin); ON; cysteine rich protein; osteonectin; BM-40; cysteine-rich protein; basement-membrane protein 40; secreted protein acidic and rich in cysteine; |
Gene ID : | 6678 |
mRNA Refseq : | NM_003118 |
Protein Refseq : | NP_003109 |
MIM : | 182120 |
UniProt ID : | P09486 |
Chromosome Location : | 5q31-q33 |
Pathway : | Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem; Senescence and Autophagy, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem; |
Function : | calcium ion binding; collagen binding; extracellular matrix binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Sparc-034M | Recombinant Mouse Sparc Protein, His-tagged | +Inquiry |
Sparc-8608M | Recombinant Mouse Sparc Protein, His (Fc)-Avi-tagged | +Inquiry |
SPARC-2503H | Recombinant Human SPARC Protein, MYC/DDK-tagged | +Inquiry |
Sparc-010M | Recombinant Mouse Sparc Protein, His-tagged | +Inquiry |
SPARC-5342R | Recombinant Rat SPARC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
SPARC-287B | Native Bovine Osteonectin | +Inquiry |
SPARC-30653TH | Native Human SPARC | +Inquiry |
◆ Lysates | ||
SPARC-2120MCL | Recombinant Mouse SPARC cell lysate | +Inquiry |
SPARC-2616HCL | Recombinant Human SPARC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (5)
Ask a questionSPARC is associated with cancer progression, as it can influence tumor growth, invasion, and angiogenesis. Its expression levels in tumors are often studied for prognostic and diagnostic purposes.
Yes, SPARC is being explored as a therapeutic target for cancer. Researchers are investigating ways to modulate its activity to hinder tumor progression or enhance the efficacy of existing treatments.
SPARC expression can be detected through techniques like immunohistochemistry, Western blotting, and molecular assays. These methods help assess SPARC levels in tissues or blood samples.
SPARC plays a role in tissue repair by influencing cell-matrix interactions and modulating the extracellular environment. Its involvement in wound healing and tissue regeneration makes it a subject of interest in regenerative medicine.
Yes, there are clinical trials exploring the potential of targeting SPARC in various diseases, including cancer. These trials aim to evaluate the safety and efficacy of SPARC-modulating agents.
Customer Reviews (3)
Write a reviewThe SPARC protein finds great utility in protein electron microscopy structure analysis, consistently delivering exceptional results.
Its remarkable sensitivity and specificity make it a valuable tool for accurate and robust data analysis, bolstering the credibility of research outcomes.
Notably, it exhibits exceptional performance in ELISA assays, providing reliable and precise results in the detection and quantification of target molecules.
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