Recombinant Human SPTLC1 Protein, Myc/DDK-tagged
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| Cat.No. : | SPTLC1-01H |
| Product Overview : | Recombinant protein of human serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T. |
| Description : | This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. |
| Source : | HEK293T |
| Species : | Human |
| Tag : | C-Myc/DDK |
| Molecular Mass : | 52.6 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
| SDS-PAGE : |
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| Gene Name : | SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Homo sapiens (human) ] |
| Official Symbol : | SPTLC1 |
| Synonyms : | SPTLC1; serine palmitoyltransferase long chain base subunit 1; HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1; serine palmitoyltransferase 1; long chain base biosynthesis protein 1; serine C-palmitoyltransferase; serine-palmitoyl-CoA transferase 1; EC 2.3.1.50 |
| Gene ID : | 10558 |
| mRNA Refseq : | NM_006415 |
| Protein Refseq : | NP_006406 |
| MIM : | 605712 |
| UniProt ID : | O15269 |
◆ Recombinant Protein
| Sptlc1-6117M | Recombinant Mouse Sptlc1 Protein, Myc/DDK-tagged | +Inquiry |
| Sptlc1-680M | Recombinant Mouse Sptlc1 Protein, His-tagged | +Inquiry |
| Sptlc1-02M | Recombinant Mouse Sptlc1 Protein, Myc/DDK-tagged | +Inquiry |
| SPTLC1-2676Z | Recombinant Zebrafish SPTLC1 | +Inquiry |
| SPTLC1-30887TH | Recombinant Human SPTLC1, His-tagged | +Inquiry |
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◆ Lysates
| SPTLC1-1485HCL | Recombinant Human SPTLC1 293 Cell Lysate | +Inquiry |
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