Recombinant Human SPTLC1 Protein, Myc/DDK-tagged

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Recombinant Human SPTLC1 Protein, Myc/DDK-tagged

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Cat.No. : SPTLC1-01H
Product Overview : Recombinant protein of human serine palmitoyltransferase, long chain base subunit 1 (SPTLC1), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T.
Description : This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Source : HEK293T
Species : Human
Tag : C-Myc/DDK
Molecular Mass : 52.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
SDS-PAGE :

Gene Name : SPTLC1 serine palmitoyltransferase long chain base subunit 1 [ Homo sapiens (human) ]
Official Symbol : SPTLC1
Synonyms : SPTLC1; serine palmitoyltransferase long chain base subunit 1; HSN1; LBC1; LCB1; SPT1; SPTI; HSAN1; serine palmitoyltransferase 1; long chain base biosynthesis protein 1; serine C-palmitoyltransferase; serine-palmitoyl-CoA transferase 1; EC 2.3.1.50
Gene ID : 10558
mRNA Refseq : NM_006415
Protein Refseq : NP_006406
MIM : 605712
UniProt ID : O15269

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