Recombinant Human STAT2 Protein (Glu616-Ser849), N-His tagged

Cat.No. : STAT2-6361H
Product Overview : Recombinant human STAT2 (Glu616-Ser849) fused with the N-His tag was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : N-His
Form : Lyophilized powder/frozen liquid
Molecular Mass : 29.16 kDa
Protein Length : Glu616-Ser849
Purity : > 90 % as determined by SDS-PAGE
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : 0.01M PBS, pH 7.4, 0.02 % NLS
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
SDS-PAGE:
Gene Name : STAT2 signal transducer and activator of transcription 2, 113kDa [ Homo sapiens (human) ]
Official Symbol : STAT2
Synonyms : STAT2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2; STAT113; interferon alpha induced transcriptional activator; P113; ISGF-3; MGC59816;
Gene ID : 6773
mRNA Refseq : NM_005419
Protein Refseq : NP_005410
MIM : 600556
UniProt ID : P52630

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is the expression of STAT2 protein altered in certain diseases? 09/21/2022

STAT2 expression can be upregulated or downregulated in different diseases, leading to dysregulated immune responses and potential susceptibility to certain infections or autoimmune conditions.

Are there any known genetic mutations associated with STAT2-related disorders? 03/31/2022

Yes, certain genetic mutations in the STAT2 gene have been linked to primary immunodeficiency disorders, impacting the body's ability to mount an effective immune response.

In what ways can the study of STAT2 protein aid in the development of novel immunotherapies? 04/16/2019

Understanding the intricate signaling pathways involving STAT2 can provide insights into potential targets for immunotherapy, offering promising avenues for the treatment of various immune-related disorders and cancers.

Can the assessment of STAT2 expression levels serve as a prognostic marker for certain viral infections? 01/18/2019

Yes, the evaluation of STAT2 expression levels can provide valuable insights into the immune status of individuals and may serve as a prognostic marker for the severity and outcome of specific viral infections.

How do polymorphisms in the STAT2 gene influence individual susceptibility to infectious diseases? 12/16/2017

Polymorphisms in the STAT2 gene can impact the individual's susceptibility to specific infectious diseases by altering the host's immune response and the ability to effectively combat pathogens.

Customer Reviews (3)

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Reviews
11/17/2022

    Their expertise and commitment to customer satisfaction are truly commendable, ensuring that I have access to the necessary resources to overcome any experimental hurdles that may arise.

    08/20/2017

      The manufacturer's outstanding technical support serves as a valuable resource, providing prompt and knowledgeable assistance whenever I encounter difficulties or require guidance.

      10/02/2016

        Its consistent performance and remarkable stability make it a reliable tool in studying various cellular processes and signaling pathways.

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