Recombinant Human STAT2
Cat.No. : | STAT2-30904TH |
Product Overview : | Recombinant full length protein (Human) |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the transcription factor STAT family.Contains 1 SH2 domain. |
Gene Name : | STAT2 signal transducer and activator of transcription 2, 113kDa [ Homo sapiens ] |
Official Symbol : | STAT2 |
Synonyms : | STAT2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2; STAT113; |
Gene ID : | 6773 |
mRNA Refseq : | NM_005419 |
Protein Refseq : | NP_005410 |
MIM : | 600556 |
Uniprot ID : | P52630 |
Chromosome Location : | 12q13.2 |
Pathway : | Adipogenesis, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; |
Function : | DNA binding; calcium ion binding; protein binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
Stat2-6169M | Recombinant Mouse Stat2 Protein, Myc/DDK-tagged | +Inquiry |
STAT2-4333R | Recombinant Rhesus Macaque STAT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT2-333H | Recombinant Human STAT2 protein, His/MBP-tagged | +Inquiry |
STAT2-332H | Recombinant Human STAT2 protein, His/MBP-tagged | +Inquiry |
Stat2-1810R | Recombinant Rat Stat2 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
STAT2-1419HCL | Recombinant Human STAT2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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