Recombinant Human STAT2 Protein, His-tagged
Cat.No. : | STAT2-151H |
Product Overview : | Recombinant Human signal transducer and activator of transcription 2(STAT2) protein, transcript variant 1(NM_005419), with a His tag, was expressed in human cells. |
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Description : | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.35, without any preservatives. |
Molecular Mass : | 97.7 kDa |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
Gene Name | STAT2 signal transducer and activator of transcription 2, 113kDa [ Homo sapiens ] |
Official Symbol | STAT2 |
Synonyms | STAT2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2; STAT113; interferon alpha induced transcriptional activator; P113; ISGF-3; MGC59816; |
Gene ID | 6773 |
mRNA Refseq | NM_005419 |
Protein Refseq | NP_005410 |
MIM | 600556 |
UniProt ID | P52630 |
Not For Human Consumption!
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