Recombinant Human STAT2 Protein, His-tagged

Cat.No. : STAT2-151H
Product Overview : Recombinant Human signal transducer and activator of transcription 2(STAT2) protein, transcript variant 1(NM_005419), with a His tag, was expressed in human cells.
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Description : The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.35, without any preservatives.
Molecular Mass : 97.7 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name STAT2 signal transducer and activator of transcription 2, 113kDa [ Homo sapiens ]
Official Symbol STAT2
Synonyms STAT2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2; STAT113; interferon alpha induced transcriptional activator; P113; ISGF-3; MGC59816;
Gene ID 6773
mRNA Refseq NM_005419
Protein Refseq NP_005410
MIM 600556
UniProt ID P52630

Not For Human Consumption!

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