Recombinant Human STAT6 Protein, His-tagged
Cat.No. : | STAT6-707H |
Product Overview : | Recombinant Human STAT6, transcript variant 2, fused with His tag at C-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
Molecular Mass : | 23.9kD |
AA Sequence : | MSHYKPEQMGKDGRGYVPATIKMTV ERDQPLPTPELQMPTMVPSYDLGMA PDSSMSMQLGPDMVPQVYPPHSHSI PPYQGLSPEESVNVLSAFQEPHLQM PPSLGQMSLPFDQPHPQGLLPCQPQ EHAVSSPDPLLCSDVTMVEDSCLSQ PVTAFPQGTWIGEDIFPPLLPPTEQ DLTKLLLEGQGESGGGSLGAQPLLQ PSHYGQSGISMSLEHHHHHH |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ] |
Official Symbol : | STAT6 |
Synonyms : | STAT6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and activator of transcription 6; D12S1644; IL 4 STAT; STAT, interleukin4-induced; transcription factor IL-4 STAT; STAT6B; STAT6C; IL-4-STAT; |
Gene ID : | 6778 |
mRNA Refseq : | NM_001178078 |
Protein Refseq : | NP_001171549 |
MIM : | 601512 |
UniProt ID : | P42226 |
Products Types
◆ Recombinant Protein | ||
STAT6-8789M | Recombinant Mouse STAT6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Stat6-6174M | Recombinant Mouse Stat6 Protein, Myc/DDK-tagged | +Inquiry |
STAT6-4335R | Recombinant Rhesus Macaque STAT6 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT6-2119H | Recombinant Human STAT6 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT6-2897H | Recombinant Human STAT6 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
STAT6-481HCL | Recombinant Human STAT6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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