Recombinant Human STAT6 Protein, MYC/DDK-tagged

• Cat.No.: STAT6-2897H
• Product Overview: Recombinant Human STAT6 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 94 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ]
• Official Symbol: STAT6
• Synonyms: D12S1644; IL-4-STAT; STAT6B; STAT6C
• Gene ID: 6778
• mRNA Refseq: NM_001178078
• Protein Refseq: NP_001171549
• MIM: 601512
• UniProt ID: P42226