Recombinant Human STAT6 Protein, MYC/DDK-tagged

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Recombinant Human STAT6 Protein, MYC/DDK-tagged

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Cat.No. : STAT6-2897H
Product Overview : Recombinant Human STAT6 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 94 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : STAT6 signal transducer and activator of transcription 6, interleukin-4 induced [ Homo sapiens ]
Official Symbol : STAT6
Synonyms : D12S1644; IL-4-STAT; STAT6B; STAT6C
Gene ID : 6778
mRNA Refseq : NM_001178078
Protein Refseq : NP_001171549
MIM : 601512
UniProt ID : P42226
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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