Recombinant Human STAU1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human STAU1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : STAU1-4103H
Product Overview : STAU1 MS Standard C13 and N15-labeled recombinant protein (NP_059347) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 63 kDa
AA Sequence : MSQVQVQVQN PSAALSGSQI LNKNQSLLSQ PLMSIPSTTS SLPSENAGRP IQNSALPSAS ITSTSAAAES ITPTVELNAL CMKLGKKPMY KPVDPYSRMQ STYNYNMRGG AYPPRYFYPF PVPPLLYQVE LSVGGQQFNG KGKTRQAAKH DAAAKALRIL QNEPLPERLE VNGRESEEEN LNKSEISQVF EIALKRNLPV NFEVARESGP PHMKNFVTKV SVGEFVGEGE GKSKKISKKN AAIAVLEELK KLPPLPAVER VKPRIKKKTK PIVKPQTSPE YGQGINPISR LAQIQQAKKE KEPEYTLLTE RGLPRRREFV MQVKVGNHTA EGTGTNKKVA KRNAAENMLE ILGFKVPQAQ PTKPALKSEE KTPIKKPGDG RKVTFFEPGS GDENGTSNKE DEFRMPYLSH QQLPAGILPM VPEVAQAVGV SQGHHTKDFT RAAPNPAKAT VTAMIARELL YGGTSPTAET ILKNNISSGH VPHGPLTRPS EQLDYLSRVQ GFQVEYKDFP KNNKNEFVSL INCSSQPPLI SHGIGKDVES CHDMAALNIL KLLSELDQQS TEMPRTGNGP MSVCGRCTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : STAU1 staufen double-stranded RNA binding protein 1 [ Homo sapiens (human) ]
Official Symbol : STAU1
Synonyms : STAU1; staufen, RNA binding protein, homolog 1 (Drosophila); STAU, staufen (Drosophila, RNA binding protein), staufen, RNA binding protein (Drosophila); double-stranded RNA-binding protein Staufen homolog 1; STAU; FLJ25010;
Gene ID : 6780
mRNA Refseq : NM_017453
Protein Refseq : NP_059347
MIM : 601716
UniProt ID : O95793

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