Recombinant Human Stromal Cell-Dreived Factor 1, His-tagged
Cat.No. : | CXCL12-64H |
- Specification
- Gene Information
- Related Products
Cat. No. : | CXCL12-64H |
Product overview : | Recombinant human SDF-1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 10.8 kDa (93aa) |
Description : | SDF-1 is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). SDF-1 is strongly chemotactic for lymphocytes andworks by its receptor CXCR4. The SDF-1+CXCR4 complex plays a significant role in the creation of metastases of neoplasms and as a response to cytostatic treatment. Identification of this complex may be a useful prognostic factor in the therapy of many types of carcinoma. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MKPVSLSYRC PCRFFESHVA RANVKHLKIL NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKR FKM |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
Purity : | > 90% by SDS - PAGE |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method ) |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | CXCL12 |
Synonyms : | PBSF; SCYB12; SDF-1a; SDF-1b; SDF1; SDF-1; SDF1A; SDF1B; TLSF; TLSF-a; TLSF-b; TPAR1; C-X-C motif chemokine 12; Pre-B cell growth-stimulating factor; Stromal cell-derived factor 1 precursor; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); stromal cell-derived factor 1; stromal cell-derived factor 1 delta; stromal cell-derived factor 1 gamma; stromal cell-derived factor 1a; CXCL12. |
Gene ID : | 6387 |
mRNA Refseq : | NM_199168 |
Protein Refseq : | NP_954637 |
MIM : | 600835 |
Uniprot ID : | P48061 |
Chromosome Location : | 10q11.1 |
Pathway : | Axon guidance, Cytokine-cytokine receptor interaction, Leukocyte transendothelial migration |
Function : | chemokine activity, chemokine activity, growth factor activity, signal transducer activity |
Products Types
◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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