Recombinant Mouse Cxcl12 protein, His-tagged
Cat.No. : | Cxcl12-42M |
Product Overview : | Recombinant mouse Cxcl12, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Cxcl12 also known as stromal cell-derived factor 1 isoform alpha. This protein acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. This protein inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Cxcl12 protein plays a protective role after myocardial infarction. It induces down-regulation and internalization of ACKR3 expressed in various cells. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol |
Molecular Mass : | 10.4kDa (91aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSKPVSLSY RCPCRFFESH IARANVKHLK ILNTPNCALQ IVARLKNNNR QVCIDPKLKW IQEYLEKALN K |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Absorbance at 280nm) |
Gene Name : | Cxcl12 chemokine (C-X-C motif) ligand 12 [ Mus musculus ] |
Official Symbol : | Cxcl12 |
Synonyms : | CXCL12; chemokine (C-X-C motif) ligand 12; stromal cell-derived factor 1; C-X-C motif chemokine 12; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; thymic lymphoma cell-stimulating factor; 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; Pbsf; Sdf1; Tlsf; Sdf1a; Sdf1b; Tlsfa; Tlsfb; Tpar1; Scyb12; AI174028; |
Gene ID : | 20315 |
mRNA Refseq : | NM_001012477 |
Protein Refseq : | NP_001012495 |
MIM : | |
UniProt ID : | |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | CXCR chemokine receptor binding; chemokine activity; cytokine activity; growth factor activity; |
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◆ Recombinant Protein | ||
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CXCL12-2160H | Recombinant Human CXCL12 Protein, GST-tagged | +Inquiry |
CXCL12-273H | Active Recombinant Human CXCL12 Protein (Val24-Asn88), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
CXCL12-1863CCL | Recombinant Cynomolgus CXCL12 cell lysate | +Inquiry |
CXCL12-3016HCL | Recombinant Human CXCL12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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