Recombinant Human TFE3 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human TFE3 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : TFE3-399H
Product Overview : TFE3 MS Standard C13 and N15-labeled recombinant protein (NP_006512) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 61.5 kDa
AA Sequence : MSHAAEPARD GVEASAEGPR AVFVLLEERR PADSAQLLSL NSLLPESGIV ADIELENVLD PDSFYELKSQ PLPLRSSLPI SLQATPATPA TLSASSSAGG SRTPAMSSSS SSRVLLRQQL MRAQAQEQER RERREQAAAA PFPSPAPASP AISVVGVSAG GHTLSRPPPA QVPREVLKVQ THLENPTRYH LQQARRQQVK QYLSTTLGPK LASQALTPPP GPASAQPLPA PEAAHTTGPT GSAPNSPMAL LTIGSSSEKE IDDVIDEIIS LESSYNDEML SYLPGGTTGL QLPSTLPVSG NLLDVYSSQG VATPAITVSN SCPAELPNIK REISETEAKA LLKERQKKDN HNLIERRRRF NINDRIKELG TLIPKSSDPE MRWNKGTILK ASVDYIRKLQ KEQQRSKDLE SRQRSLEQAN RSLQLRIQEL ELQAQIHGLP VPPTPGLLSL ATTSASDSLK PEQLDIEEEG RPGAATFHVG GGPAQNAPHQ QPPAPPSDAL LDLHFPSDHL GDLGDPFHLG LEDILMEEEE GVVGGLSGGA LSPLRAASDP LLSSVSPAVS KASSRRSSFS MEEESTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : TFE3 transcription factor binding to IGHM enhancer 3 [ Homo sapiens (human) ]
Official Symbol : TFE3
Synonyms : TFE3; transcription factor binding to IGHM enhancer 3; transcription factor E3; bHLHe33; member A; TFEA; transcription factor E family; Transcription factor for IgH enhancer; transcription factor E family, member A; class E basic helix-loop-helix protein 33; RCCP2; RCCX1;
Gene ID : 7030
mRNA Refseq : NM_006521
Protein Refseq : NP_006512
MIM : 314310
UniProt ID : P19532

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