Recombinant Human TFPI protein, His-Avi-tagged, Biotinylated
Cat.No. : | TFPI-646HB |
Product Overview : | Biotinylated Recombinant Human TFPI Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal. It contains Asp29-Lys282. |
- Specification
- Gene Information
- Related Products
Description : | Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22μm filtered solution in PBS(pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 32.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Protein length : | Asp29-Lys282 |
Endotoxin : | Less than 0.05 EU per μg by the LAL method. |
Purity : | >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | TFPI |
Official Symbol : | TFPI |
Synonyms : | LACI, TFPI1, EPI, TFI |
Gene ID : | 7035 |
mRNA Refseq : | NM_001032281.3 |
Protein Refseq : | NP_001027452.1 |
MIM : | 152310 |
UniProt ID : | P10646 |
Products Types
◆ Recombinant Protein | ||
TFPI-751H | Recombinant Human TFPI Protein, Biotinylated | +Inquiry |
Tfpi-9155M | Recombinant Mouse Tfpi Protein, His (Fc)-Avi-tagged | +Inquiry |
TFPI-753R | Recombinant Rhesus macaque TFPI Protein | +Inquiry |
Tfpi-6383M | Recombinant Mouse Tfpi Protein, Myc/DDK-tagged | +Inquiry |
TFPI-752H | Recombinant Human TFPI Protein | +Inquiry |
◆ Lysates | ||
TFPI-2843MCL | Recombinant Mouse TFPI cell lysate | +Inquiry |
TFPI-2746HCL | Recombinant Human TFPI cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMonitoring TFPI levels is crucial in patients with a history of thrombotic events, individuals at high risk of clotting disorders, and those undergoing anticoagulant therapy.
Research suggests that manipulating TFPI levels might be explored to reduce thrombotic complications in surgical and medical settings, potentially improving patient outcomes.
Manipulating TFPI levels may pose challenges, as it could potentially lead to bleeding disorders. Balancing the anticoagulant effects with the risk of bleeding is a critical consideration.
TFPI has anti-inflammatory effects by inhibiting the activation of immune cells and downregulating inflammatory mediators. This dual role makes it a potential therapeutic target in conditions involving both coagulation and inflammation.
Pharmaceutical research can explore the development of drugs that either enhance or mimic the activity of TFPI, providing new avenues for anticoagulant therapies.
Customer Reviews (3)
Write a reviewThis property is particularly beneficial for long-term trials or experiments with extended durations, ensuring consistent performance throughout the entire study period.
Its purity and consistency have been extensively validated, minimizing any potential variability that could affect trial outcomes.
Their extensive technical expertise and assistance are invaluable in overcoming any challenges that may arise during the experimental process.
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