Recombinant Human TFPI protein, His-tagged, Biotinylated
Cat.No. : | TFPI-876H |
Product Overview : | Biotinylated Recombinant Human TFPI protein(Asp 29 - Lys 282), fused with His tag, was expressed in HEK293. |
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- Gene Information
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 30.0 kDa. The protein migrates as 41-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Asp 29 - Lys 282 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) [ Homo sapiens ] |
Official Symbol : | TFPI |
Synonyms : | TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); LACI; tissue factor pathway inhibitor; EPI; extrinsic pathway inhibitor; TFI; TFPI1; anti-convertin; |
Gene ID : | 7035 |
mRNA Refseq : | NM_001032281 |
Protein Refseq : | NP_001027452 |
MIM : | 152310 |
UniProt ID : | P10646 |
Products Types
◆ Recombinant Protein | ||
Tfpi-981M | Active Recombinant Mouse Tfpi protein(Met1-Lys289), His-tagged | +Inquiry |
TFPI-752H | Recombinant Human TFPI Protein | +Inquiry |
Tfpi-6383M | Recombinant Mouse Tfpi Protein, Myc/DDK-tagged | +Inquiry |
TFPI-1246H | Recombinant Human TFPI Protein, His-tagged | +Inquiry |
TFPI-707H | Recombinant Human TFPI Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
TFPI-2843MCL | Recombinant Mouse TFPI cell lysate | +Inquiry |
TFPI-2746HCL | Recombinant Human TFPI cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMonitoring TFPI levels is crucial in patients with a history of thrombotic events, individuals at high risk of clotting disorders, and those undergoing anticoagulant therapy.
Research suggests that manipulating TFPI levels might be explored to reduce thrombotic complications in surgical and medical settings, potentially improving patient outcomes.
Manipulating TFPI levels may pose challenges, as it could potentially lead to bleeding disorders. Balancing the anticoagulant effects with the risk of bleeding is a critical consideration.
TFPI has anti-inflammatory effects by inhibiting the activation of immune cells and downregulating inflammatory mediators. This dual role makes it a potential therapeutic target in conditions involving both coagulation and inflammation.
Pharmaceutical research can explore the development of drugs that either enhance or mimic the activity of TFPI, providing new avenues for anticoagulant therapies.
Customer Reviews (3)
Write a reviewThis property is particularly beneficial for long-term trials or experiments with extended durations, ensuring consistent performance throughout the entire study period.
Its purity and consistency have been extensively validated, minimizing any potential variability that could affect trial outcomes.
Their extensive technical expertise and assistance are invaluable in overcoming any challenges that may arise during the experimental process.
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