"TGFBR2" Related Products

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Recombinant Human TGFBR2 Protein, MYC/DDK-tagged

Cat.No.: TGFBR2-703H
Product Overview: Recombinant human TGFBR2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass: 62 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: transforming growth factor beta receptor 2[ Homo sapiens ]
Official Symbol: TGFBR2
Synonyms: AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFR-2
Gene ID: 7048
mRNA Refseq: NM_003242.5
Protein Refseq: NP_003233.4
MIM: 190182
UniProt ID: P37173

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