Recombinant Human TGFBR2 Protein, MYC/DDK-tagged TGFBR2-703H

Recombinant Human TGFBR2 Protein, MYC/DDK-tagged

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Recombinant Human TGFBR2 Protein, MYC/DDK-tagged

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Cat.No. : TGFBR2-703H
Product Overview : Recombinant human TGFBR2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 62 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : transforming growth factor beta receptor 2[ Homo sapiens ]
Official Symbol : TGFBR2
Synonyms : AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFR-2
Gene ID : 7048
mRNA Refseq : NM_003242.5
Protein Refseq : NP_003233.4
MIM : 190182
UniProt ID : P37173
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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